Review on Bioactive Compound of Pomegranate peel and their Role Child Nutrition and Immunity

Abstract

Source of biologically active compounds such as polyphenols (punicalagin, ellagic acid), flavonoids, tannins, alkaloids, terpenoids, dietary fiber, and essential vitamins. These compounds possess strong antioxidant, anti-inflammatory, antimicrobial, and immunomodulatory properties that contribute significantly to human health. This review highlights the nutritional and therapeutic relevance of these bioactives, with special emphasis on their potential benefits in child nutrition and immunity. Evidence from various in-vitro, in-vivo, and clinical studies shows that pomegranate peel enhances digestive health, improves nutrient absorption, and supports gut microbiota, all of which are critical during childhood growth. Its strong antioxidant capacity helps protect developing tissues from oxidative damage, while its immunomodulatory actions strengthen innate and adaptive immune responses, reducing susceptibility to infections in children. The review concludes that pomegranate peel is a low-cost, safe, and promising natural source for developing functional foods and nutraceuticals aimed at improving pediatric nutrition and immunity. However, more child-specific clinical research is required to establish optimal doses and formulations.